Agilent 1290 Infinity II HPLC System – Introduction

The Agilent 1290 Infinity II HPLC System is a high-performance liquid chromatography platform developed by Agilent Technologies for advanced analytical separations requiring exceptional speed, sensitivity, precision, and flexibility. As one of Agilent’s flagship UHPLC (Ultra High Performance Liquid Chromatography) systems, the 1290 Infinity II delivers outstanding chromatographic performance for pharmaceutical analysis, biotechnology research, food testing, environmental analysis, chemical research, and quality control applications.

The Agilent 1290 Infinity II HPLC System is designed to provide ultra-high-pressure operation, enabling faster separations, higher resolution, and improved analytical efficiency compared with conventional HPLC systems. With a maximum pressure capability of up to 1300 bar, the system supports advanced UHPLC columns with smaller particle sizes, allowing laboratories to achieve excellent peak separation and shorter analysis times while reducing solvent consumption.

A key feature of the Agilent 1290 Infinity II platform is its modular architecture. The system can be configured with various modules, including the 1290 Infinity II High-Speed Pump, Multisampler, Vialsampler, Multicolumn Thermostat, Diode Array Detector (DAD), Variable Wavelength Detector (VWD), Fluorescence Detector (FLD), Refractive Index Detector (RID), and Evaporative Light Scattering Detector (ELSD). This flexibility allows users to customize the system according to specific analytical requirements.

The Agilent 1290 Infinity II Flexible Pump provides highly accurate solvent delivery with excellent flow precision and gradient reproducibility. Advanced pump technology minimizes pulsation and improves baseline stability, making it suitable for demanding applications such as impurity profiling, trace analysis, and complex sample characterization.

The 1290 Infinity II Multisampler offers reliable automated sample injection with high precision and throughput. It supports large sample capacities and advanced injection modes, helping laboratories increase productivity while maintaining excellent analytical reproducibility.

The system incorporates Agilent’s advanced temperature control technologies to maintain stable column conditions during analysis. Precise column temperature management improves retention time reproducibility and enhances separation performance, especially for temperature-sensitive applications.

The Agilent 1290 Infinity II is fully integrated with Agilent OpenLab CDS and ChemStation software, providing complete instrument control, data acquisition, chromatographic analysis, quantification, reporting, and compliance management. These software platforms support regulated laboratory environments, including pharmaceutical quality control and research applications.

The 1290 Infinity II HPLC System is widely used in pharmaceutical development, biopharmaceutical analysis, metabolomics, environmental testing, food safety, and academic research. Its combination of ultra-high pressure capability, modular flexibility, and excellent analytical performance makes it a preferred solution for laboratories requiring high-resolution chromatographic analysis.

Due to its advanced technology, reliability, and long service life, refurbished Agilent 1290 Infinity II HPLC Systems are highly valued in the global used laboratory equipment market. They provide laboratories with access to premium UHPLC performance while offering a cost-effective alternative to purchasing new instrumentation.

Agilent 1290 Infinity II HPLC System Technical Specifications