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Detailed Introduction
The KrosFlow TFF System with Balance, Peri Pump, and Accessories is a versatile laboratory-scale tangential flow filtration (TFF) platform designed for efficient concentration, purification, and buffer exchange of biological samples. It is widely used in biotechnology, pharmaceutical research, protein purification, vaccine development, and laboratory process development. The system provides a flexible and reliable solution for researchers who need precise control over filtration processes involving proteins, antibodies, nucleic acids, viruses, nanoparticles, and other biomolecules.
Tangential flow filtration technology differs from traditional dead-end filtration by continuously circulating the sample across the membrane surface rather than forcing the entire sample directly through the filter. This cross-flow mechanism helps reduce membrane fouling, improves filtration efficiency, and enables gentle processing of sensitive biological materials. The KrosFlow TFF System is designed to maintain product quality while achieving high recovery rates.
The system configuration includes a KrosFlow TFF unit, balance system, peristaltic pump, and related accessories, providing an integrated solution for laboratory-scale filtration workflows. The peristaltic pump delivers accurate and adjustable flow control, allowing users to optimize transmembrane pressure and circulation rates according to different sample characteristics. The integrated balance helps monitor sample weight changes during processing, improving process control and reproducibility.
The KrosFlow TFF System supports a wide range of membrane modules and filtration areas, making it suitable for various applications from small-scale research experiments to process development studies. Researchers can perform concentration and diafiltration steps efficiently, reducing processing time while maintaining sample integrity.
Typical applications include recombinant protein concentration, monoclonal antibody processing, virus purification, extracellular vesicle preparation, cell culture media processing, and laboratory-scale bioprocess optimization. The system is especially valuable for laboratories developing scalable purification processes before moving to larger production platforms.
A refurbished KrosFlow TFF System with Balance, Peri Pump, and Accessories can provide an economical option for laboratories seeking professional tangential flow filtration capability. Before use, refurbished systems should be inspected and tested for pump performance, tubing condition, balance accuracy, pressure monitoring functions, and overall system operation.
With its flexible configuration, accurate flow control, and compatibility with modern bioprocess applications, the KrosFlow TFF System is an excellent choice for research laboratories requiring reliable and efficient small-scale filtration solutions.
| Parameter | Specification |
|---|---|
| Product Name | KrosFlow TFF System with Balance, Peri Pump and Accessories |
| Product Type | Laboratory Tangential Flow Filtration System |
| Main Technology | Tangential Flow Filtration (TFF) |
| System Configuration | TFF unit + balance + peristaltic pump + accessories |
| Pump Type | Peristaltic pump |
| Flow Control | Adjustable circulation flow rate |
| Filtration Mode | Cross-flow filtration |
| Membrane Compatibility | Compatible with laboratory TFF membrane modules |
| Applications | Concentration, purification, diafiltration, buffer exchange |
| Sample Types | Proteins, antibodies, nucleic acids, viruses, nanoparticles, biomolecules |
| Balance Function | Real-time weight monitoring during processing |
| Pump Control | Precise liquid circulation control |
| Process Monitoring | Flow, pressure, and sample volume monitoring |
| Operating Scale | Laboratory and process development scale |
| Recovery Performance | High product recovery with reduced sample loss |
| Membrane Fouling Control | Reduced fouling through continuous cross-flow operation |
| Typical Industries | Biotechnology, pharmaceutical, academic research |
| Installation Type | Laboratory benchtop system |
| Accessories Included | Tubing, connectors, holders, and related filtration accessories |
| Maintenance Requirement | Routine cleaning and tubing replacement |
| Condition Options | New / Refurbished / Used |
The KrosFlow TFF System with Balance, Peri Pump, and Accessories provides researchers with a practical and flexible platform for laboratory-scale bioprocessing. Combining accurate pumping control, reliable filtration performance, and easy operation, it is widely recognized as an effective tool for modern biological sample preparation and purification workflows.
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