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Agilent 1260 Infinity HPLC include: G1311B 1260 Quat Pump, G1329B 1260 Autosampler (ALS)

Brief Description:Agilent 1260 Infinity High-Performance Liquid Chromatography (HPLC) system is a robust and versatile platform designed for accurate, reliable, and high-throughput analytical applications.

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Detailed Introduction

Agilent 1260 Infinity High-Performance Liquid Chromatography (HPLC) system is a robust and versatile platform designed for accurate, reliable, and high-throughput analytical applications. This configuration, including the G1311B 1260 Quaternary Pump and G1329B 1260 Autosampler (ALS), provides laboratories with the precision and flexibility needed for pharmaceutical quality control, environmental testing, food analysis, and chemical research.

The G1311B Quaternary Pump ensures precise and reproducible gradient formation across multiple solvents, supporting complex separation methods and enhancing analytical performance. It operates with low pulsation, providing a stable baseline for sensitive detectors and ensuring high reproducibility for routine and method-development applications.

The G1329B Autosampler (ALS) is designed for high-precision, automated sample injection. With programmable injection volumes, a large sample tray, and minimal carryover, it allows for high-throughput workflows while maintaining sample integrity. The combination of the Quaternary Pump and Autosampler ensures seamless operation and reliable results across multiple analytical runs.

Key Features

  • Quaternary Pump (G1311B): Delivers accurate gradient mixing of up to four solvents with low pulsation and high pressure tolerance. Ideal for method development and routine QC.

  • Autosampler (G1329B ALS): High-precision injection with programmable volumes and automated sample tray handling. Supports up to 100 vials with standard racks.

  • Modular Flexibility: Compatible with a wide range of detectors including Diode Array (DAD), Variable Wavelength (VWD), and Refractive Index (RID).

  • Software Integration: Controlled via Agilent OpenLAB CDS or ChemStation software for method development, data acquisition, and secure compliance with 21 CFR Part 11.

  • Reliable Performance: Designed for continuous operation with minimal downtime, ideal for high-volume laboratories.

Advantages of This Configuration

  • High reproducibility and precision across repeated analyses.

  • Simplified sample handling through automated injection, reducing human error.

  • Enhanced gradient control for complex separations and method flexibility.

  • Modular design allows future upgrades of detectors, column compartments, or additional modules.

  • Cost-effective and sustainable solution for laboratories seeking robust HPLC performance.

Typical Applications

  • Pharmaceutical QC and formulation analysis

  • Environmental monitoring of water and soil samples

  • Food and beverage quality testing

  • Chemical and polymer analysis

  • Academic and research laboratories requiring routine and high-precision HPLC measurements

Agilent 1260 Infinity HPLC Specifications

Component Specification
Pump Model G1311B Quaternary Pump
Solvent Channels 4 (Quaternary gradient)
Flow Rate Range 0.001 – 5.0 mL/min
Maximum Pressure 600 bar / 8700 psi
Autosampler Model G1329B ALS
Injection Volume 0.1 – 100 µL
Sample Capacity Up to 100 vials (standard 2 mL)
Autosampler Precision ±0.5% RSD
Detector Compatibility DAD, VWD, RID
Software Agilent OpenLAB CDS / ChemStation
Column Temperature Control Up to 80°C
Compliance 21 CFR Part 11 Ready
Dimensions (H x W x D) 37 x 44 x 60 cm (varies by module configuration)
Weight Approx. 55 kg

Conclusion

The Agilent 1260 Infinity HPLC with G1311B Quaternary Pump and G1329B Autosampler (ALS) is a highly reliable and flexible liquid chromatography solution for laboratories requiring precision, reproducibility, and automation. Its modular design allows seamless integration with various detectors and column compartments, while the combination of low-pulsation gradient pumping and high-precision sample injection ensures accurate results across multiple applications.

This configuration is ideal for pharmaceutical, environmental, food, and chemical laboratories, providing a cost-effective yet high-performance HPLC solution. By integrating advanced software control and automation, laboratories can optimize workflow efficiency, reduce human error, and maintain consistent analytical quality for routine and research applications.

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